Evidence

Alerts

The latest important research summarised

Short summaries of the latest health research presented in plain English to promote use of research by all members of society.

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First-line chemotherapy for ovarian cancer given once every three weeks may preserve quality of life

Women with a new diagnosis of ovarian cancer receiving weekly chemotherapy may have reduced quality of life compared to those receiving treatment every three weeks because the more frequent treatment may cause long-lasting nerve damage. Ovarian cancer is usually treated every three weeks with chemotherapy containing the medicines carboplatin and paclitaxel. A study in Japan ...

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Missed miscarriage should be treated with mifepristone plus misoprostol rather than misoprostol alone

A combination of two drugs – mifepristone and misoprostol – was more effective than mifepristone alone for treating missed miscarriage. A large, multi-centre trial found that women given the combination were more likely to have completed their miscarriage within a week, and less likely to need follow-up surgery. During a miscarriage of pregnancy, the baby ...

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Ongoing pain after knee replacement: people need support and encouragement to seek help

People with ongoing pain after knee replacement surgery may experience a sense of futility and believe nothing more can be done. A new study found that that one in five people report ongoing pain after knee replacement surgery, but many do not seek help in dealing with their pain. The researchers say that improvements in ...

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Womb cancer could be detected early with an inexpensive new blood test

A simple, low-cost blood test offers great potential as a tool for diagnosing womb cancer, and for screening high-risk women. The test gives almost instant results and in a new study, it picked up changes in the womb that could lead to cancer (pre-cancerous growths). In the UK, womb cancer is the fourth most common ...

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INCLUDE Roadmap can help researchers make trials more inclusive

Many groups – such as women, older people and ethnic minorities – are under-served in clinical trials. An NIHR project aims to ensure that health research includes the people who most need it. The project is called Innovations in Clinical Trial Design and Delivery for the Under-served (INCLUDE); the current research formed the first phase ...

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Artificial intelligence can predict the development of a leading cause of blindness

Artificial intelligence (AI) predicted the development of a leading cause of blindness in new research. A collaboration between Moorfields Eye Hospital in London and Google’s DeepMind and Google Health found that AI predicted the development of wet age-related macular degeneration (wet-AMD) more accurately than clinicians. Wet-AMD can lead to rapid and severe loss of sight. ...

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Befriending programmes for people with psychosis can be challenging but beneficial to both parties

Befriending programmes are designed to help people who are likely to be socially isolated. This could be due to illness, including mental illness, or old age. Befrienders are often volunteers who make a commitment to have regular meetings with an individual they are put in touch with, often via a service. People with psychosis are ...

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National infection control campaigns led to a rapid decline in superbug infections in UK intensive care units

In the early 2000s, bacteria that are resistant to antibiotics were widespread in UK hospitals and a strain of methicillin-resistant Staphylococcus aureus (MRSA) posed a major threat to public health. This led to nationwide infection control programmes in the mid-2000s, with a rapid decline in rates in NHS hospitals over the following decade. This study ...

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The glaucoma patients most at risk of sight loss were identified in a new study

People with glaucoma in both eyes, high pressure in the eyes and small amounts of bleeding in the eye (disc haemorrhages) have an increased risk of sight loss. These risk factors for sight loss were revealed in new analysis of study data. Glaucoma is a common eye condition in which the optic nerve connecting the ...

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British-Bangladeshi parents offer better nutrition to their children when interventions involve the community

Participants discuss the Nurture Early for Optimal Nutrition (NEON) study.  The video transcript is available here.   Efforts to help parents feed and care for young children should be developed with the input and assistance of relevant ethnic communities, a new study shows. Different generations within the British-Bangladeshi population of East London offered key information ...

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