Evidence
Alert

Measles vaccine still effective if given to infants under nine months old

A first vaccination dose against measles is a safe and somewhat effective option if given to infants earlier than usual, and before the age of nine months. However, vaccine effectiveness does increase when administered at older ages, as currently. Two doses of measles-containing vaccines are recommended as part of a childhood immunisation programme. In countries ...

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Herpes zoster vaccine reduces chances of shingles after stem cell transplants

A non-live vaccine against herpes zoster provides good, though partial protection for adults undergoing autologous (using the patient’s own) stem cell transplant for treatment of blood cancers. These people cannot use the usual live vaccine, because of their suppressed immune system. An industry-funded trial of the vaccine involved 1,846 patients from 28 countries, including the ...

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Pneumococcal vaccines for people with COPD reduce their chance of catching pneumonia

Pneumococcal vaccines reduce the risk of community-acquired pneumonia in people with moderate to severe chronic obstructive pulmonary disease (COPD). Pneumococcal vaccination is currently recommended for people with COPD and other respiratory diseases. However, until now there has been a lack of data whether it actually improves outcomes in these groups. This updated Cochrane review identified ...

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Rotavirus vaccine estimated to have saved the NHS £12.5 million a year

The introduction of the rotavirus vaccine in July 2013 has reduced rates of infectious diarrhoea (acute gastroenteritis) in children up to five years by 15%, with a 41% reduction during February to April, when rotavirus incidence is traditionally high. This NIHR-funded study used time series data to calculate the fall in infectious diarrhoea episodes after ...

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Flu vaccine reduces deaths for people with type 2 diabetes

Flu vaccination helps prevent some deaths, serious strokes, heart failure and pneumonia in people with type 2 diabetes. Vaccination is linked to less hospital admissions for these reasons, but there is no link to rates of admissions for heart attack. The results come from a reliable population-based study that looked back at the general practice ...

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Better access to healthcare for Gypsy, Roma and Traveller communities is key to increasing vaccination rates: research makes five recommendations

Better access to healthcare services is the most important step in improving vaccination rates for people in Gypsy, Roma and Traveller communities. New research suggests that easier access is more important than addressing beliefs about vaccine safety or the need for vaccination. Researchers set up a series of workshops for healthcare providers and representatives of ...

Collection

Clinical decision support tools

Clinical decision support tools aim to improve healthcare delivery by enhancing decision making through the provision of targeted health information. The evolution of clinical decision support tools has been boosted by the introduction of new technologies, and their evaluation as useful resources continues to be an area of high interest for health professionals. This Collection ...

Themed Review

Living with Covid19

A dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid). Key Messages Introduction What are we aiming to achieve with our Living with Covid19 review? Drawing on people’s experience How many people live with ongoing Covid19? Symptoms Diagnostic uncertainty Research into living with Covid19 Capturing the experience of ‘Long Covid’ Services ...

Alert

Uptake of shingles vaccination is more likely if proactively offered in primary care

The shingles vaccination programme is intended for people aged between 70 and 80 years, but uptake in this group has been low. This survey found that people were more likely to have had the vaccine if it was proactively offered by a GP or nurse. The survey was completed by 536 individuals born in 1934 ...

Collection

Nine ways research could save the NHS money

Nine ways research could save the NHS money In this highlight, we have carefully selected nine NIHR Signals that show how research could help to save the NHS money. This collection covers a range of treatments and initiatives that are cost effective for the NHS. You can find out more about Signals or read the latest on the Discover Portal. ...

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