Evidence
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New tool for assessing the severity of type 2 diabetes could help personalise treatment and improve outcomes

A new severity scoring system for type 2 diabetes may be better at identifying patients at risk of declining health than the current commonly used blood test. The Diabetes Severity Score (DISSCO) is a computer algorithm that combines information routinely collected in primary care. Researchers found that a higher DISSCO score was linked to an ...

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Bespoke shoes and insoles could prevent foot ulcers in people with diabetes

Shoes and insoles which are custom-made to relieve pressure on the foot could prevent ulcers in people with diabetes. Foot ulcers are a serious complication of the disease and can lead to amputation if they are not managed appropriately. Even a mild injury can cause a foot ulcer. Researchers wanted to identify design features of ...

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Damage to kidneys and eyes may start before people are diagnosed with diabetes

One in two people diagnosed with type 2 diabetes already have damage to their eyes, kidneys or heart. That damage is more likely if they had problems with blood sugar control before being diagnosed. Diabetes causes damage to blood vessels, because of poorly-controlled levels of sugar in the blood. These damaged blood vessels can lead ...

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GLP-1 drug for diabetes gives modest cardiovascular benefits compared with placebo

Taking a glucagon-like peptide-1 receptor (GLP-1) agonist drug lowers the likelihood of having a stroke, heart attack or dying due to cardiovascular causes by 12%. The drugs give a similar 12% reduction in overall mortality. They do not increase the risk of heart failure, very low blood sugar levels or pancreatic disease. Diabetes causes one ...

Collection

My Signals - Patients, 2019

In My Signals, health and social care staff and service users tell us what research is important to them and why they feel others need to know about it. In this collection, we asked seven members of the public to tell us which Signals have interested them most and explain why they feel the findings ...

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Losing weight following type 2 diabetes diagnosis boosts chance of remission

People who lose at least 10% of their body weight in the first year after being diagnosed with type 2 diabetes increase their chances of being in remission after five years, compared with those whose weight remains stable. Losing this achievable amount of weight over the next four years also makes remission more likely. In ...

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Boosting omega-3 fatty acid intake is unlikely to prevent type 2 diabetes

Increasing the intake of polyunsaturated fats in the diet with supplements of omega-3 fatty acids, for example, is unlikely to affect people’s risk of developing type 2 diabetes. However, this review only looked at the effect of supplements on diabetes, not wider health. This large systematic review included 83 long-term trials comparing higher and lower ...

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Smartphones may help people with diabetes manage their condition better

People with type 2 diabetes using smartphone apps or message services feel more confident about their ability to manage their condition, are more likely to engage in self-care activities and have a better quality of life. Smartphone self-management technologies can be split into two main types: applications where users can record data and view information, ...

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Thyroid hormone treatment does not help adults with mildly abnormal thyroid tests

There appears to be no benefit from treating adults with subclinical hypothyroidism. Treatment has no effect on quality of life or symptoms compared with placebo or no treatment. Thyroid function tests are commonly performed in general practice for patients who present with a range of symptoms, including fatigue or tiredness. When subclinical hypothyroidism is detected, ...

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Repeat thyroid function tests for healthy older people are not needed

Older adults with normal thyroid function or subclinical thyroid dysfunction show notable long-term stability of their thyroid hormone levels. This suggests that it is safe for GPs not to routinely retest older adults unless they have risk factors or develop clinical symptoms of overt thyroid dysfunction. Over five years, about 0.2% older adults with normal ...

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