Evidence
Alert

Brain and nerve complications are more common than expected in younger patients with severe COVID-19

People aged under 60 who are hospitalised with COVID-19 are more likely than expected to experience severe psychiatric symptoms. Research found that altered mental states such as psychosis are being reported in these younger patients.  It confirmed that strokes and other neurological symptoms are common in severe COVID-19. An initial study included 153 cases reported ...

Alert

A decision aid may help people with newly-diagnosed multiple sclerosis consider their options for treatment

When first diagnosed with multiple sclerosis (MS), people may feel overwhelmed with information, or too shocked by the diagnosis to fully engage with decisions about treatment. New research found that decision aids may help them to understand their condition and make decisions that are right for them.  Treatments for people with MS can improve long-term ...

Alert

People with late-stage Parkinson’s need personalised, flexible, home-based care

People with late-stage Parkinson’s disease have complex, unmet needs, but their voices are often not heard, say researchers. One-on-one interviews revealed that people in this group need more flexible, personalised care at home and in the community to help them manage their symptoms and maintain control over their condition. The research also highlights the need ...

Alert

Loneliness, but not social isolation, predicts development of dementia in older people

Older people who feel lonely and have few close relationships may have an increased chance of developing dementia. Perhaps surprisingly, being socially isolated with few or infrequent social contacts does not seem to predict dementia risk, researchers found. This study was carried out before the coronavirus pandemic but the findings are relevant now, when the ...

Alert

Melatonin shows potential for reducing delirium among older people after surgery

Taking melatonin around the time of surgery is linked with lower odds of delirium onset in older people, compared with placebo or no treatment. In a systematic review and meta-analysis, around 15% of the melatonin group developed delirium after surgery compared with around 20% of the comparison group. Delirium is an acute state of mental ...

Themed Review

Better Health and Care for All

Download the PDF  Foreword The last thirty years has seen big changes in health and social care to support people with learning disabilities. This includes a move from long-stay hospitals to supporting more people to live well in the community. But it is not easy – and we still have a long way to go ...

Alert

Occupational therapy at home may benefit people with dementia and their carers

Multiple occupational therapy sessions, provided in a person with dementia’s own home, improve their ability to carry out daily activities, compared with usual care. Improvements are also seen in behavioural and psychological symptoms and their quality of life. In addition, carers report feeling less distress, and a better quality of life. This study was a systematic ...

Themed Review

Better Health and Care for All - Easy Read

Health and Care services for people with learning disabilities Easy read summary     This Report is about research into learning disabilities. This research was paid for by the National Institute for Health Research. This is the Easy Read Summary. There is more information in the full report.       Contents Why is this report ...

Alert

Tranexamic acid is safe to use following mild-to-moderate traumatic brain injury and reduces deaths

In people with mild-to-moderate traumatic brain injury, tranexamic acid (a drug which reduces bleeding) given within three hours of injury reduces the risk of death by 22%. This effect is seen in a subgroup of those who are less severely affected. This NIHR-funded multi-centre international trial randomised 12,737 adults with intracranial bleeding to receive either ...

Collection

My Signals - Patients, 2019

In My Signals, health and social care staff and service users tell us what research is important to them and why they feel others need to know about it. In this collection, we asked seven members of the public to tell us which Signals have interested them most and explain why they feel the findings ...

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