Evidence
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Outcomes similar for full or partial hip replacement after hip fracture

For older people with hip fracture, the choice between full or partial hip replacement does not greatly influence outcomes. In this trial, approximately 8% of patients having each operation required further surgery within a 24-month period. Mortality rates were also similar at around 13%. This multinational trial included 1,495 adults aged over 50 with a hip ...

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Increasing omega-3 intake does not prevent depression or anxiety

Increasing intake of polyunsaturated fats, for example with omega-3 fatty acid supplements, has little or no effect in preventing the onset of depression or anxiety symptoms in people without these conditions, but who might be at risk. These findings support dietary advice that omega-3 supplements are not needed in healthy people. This review also highlights ...

Themed Review

Better Health and Care for All - Easy Read

Health and Care services for people with learning disabilities Easy read summary     This Report is about research into learning disabilities. This research was paid for by the National Institute for Health Research. This is the Easy Read Summary. There is more information in the full report.       Contents Why is this report ...

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Universal ultrasound in late pregnancy did not reduce serious harms to babies

Offering all women third trimester ultrasounds did not reduce the rate of serious illness or death in babies in the first week of life. Monitoring fetal growth is part of routine antenatal care, using regular tape measurements from the pubic bone to the top of the uterus. To date, it has been unclear whether also ...

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Whole-school programme can have a small effect on reducing bullying in secondary schools

An anti-bullying intervention trialled at 20 UK secondary schools resulted in a reduction in bullying incidents at school. The ‘Learning Together’ initiative was funded by the NIHR and designed to modify the school environment and provide social and emotional support. The trial took place over three years and involved around 3,000 pupils who were 11 ...

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Impact of online or app-based assessment for urgent health problems largely unclear

Relatively little robust evidence exists on the impact of online or app-based health assessments for people seeking urgent care. The available evidence suggests that these services are not as good at making diagnoses as health professionals; though it is not clear whether this is a useful benchmark. The ‘NHS 111 Online’ service for symptom checking ...

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Measles vaccine still effective if given to infants under nine months old

A first vaccination dose against measles is a safe and somewhat effective option if given to infants earlier than usual, and before the age of nine months. However, vaccine effectiveness does increase when administered at older ages, as currently. Two doses of measles-containing vaccines are recommended as part of a childhood immunisation programme. In countries ...

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Antenatal MRI can aid ultrasound when fetal brain abnormality is suspected

In utero magnetic resonance imaging (iuMRI) can provide a more accurate diagnosis when used after ultrasound in pregnancy. Adding iuMRI when a brain abnormality is suspected but unclear from ultrasound could help clinicians provide better prognostic advice and support to parents during pregnancy. This NIHR-funded cohort study compared ultrasound and iuMRI in 570 women at ...

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‘Care navigation’ is being widely adopted in primary care, but in varying ways

Clinical Commissioning Groups (CCGs) in England are implementing care navigation in primary care to help people with non-medical issues to access alternative services. This ‘social prescribing’, facilitated by nominated care navigators, also aims to reduce the pressure on general practice, and forms part of the NHS Long Term Plan. This NIHR-funded study shows that the ...

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GLP-1 drug for diabetes gives modest cardiovascular benefits compared with placebo

Taking a glucagon-like peptide-1 receptor (GLP-1) agonist drug lowers the likelihood of having a stroke, heart attack or dying due to cardiovascular causes by 12%. The drugs give a similar 12% reduction in overall mortality. They do not increase the risk of heart failure, very low blood sugar levels or pancreatic disease. Diabetes causes one ...

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