Evidence

Alerts

The latest important research summarised

Short summaries of the latest health research presented in plain English to promote use of research by all members of society.

Alert

NHS managers need support to use tools to ensure safe nurse staffing levels

Workforce planning technologies can help NHS managers plan for safe nurse staffing levels, but only with proper support and tools that are designed with good understanding of local needs. Tools also need to give easy access to standardised information such as staff availability and costs. NHS Trusts need to be open to information sharing and ...

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Reconfiguring neonatal services balances survival chances against increased travel for families

Centralising services so that all babies are delivered in high-volume neonatal units could more than halve the number of units from 161 to 72, meaning that more parents would need to travel above 30 minutes. However, ensuring that all very preterm and low birthweight babies are cared for in high-volume neonatal intensive care units would reduce ...

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Early cooling provides no benefit following traumatic brain injury

Deliberate cooling (prophylactic hypothermia) in the early management of traumatic brain injury does not improve neurological outcomes at six months. Inducing hypothermia may also increase the risk of pneumonia. Hypothermia (33-35oC) is sometimes induced to try and limit brain damage in people with severe head injuries. However, evidence for its safety and effectiveness has been ...

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Warfarin and newer anticoagulants equally effective for long-term treatment of blood clots

Warfarin and newer anticoagulants work equally well to prevent blood clots in extended treatment after venous thromboembolism. One clot is prevented for every 15 people receiving either anticoagulant. Aspirin is ineffective. Following venous thromboembolism – a blood clot in the deep leg veins (deep vein thrombosis) or lungs (pulmonary embolism) – anticoagulant treatment is given ...

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A care package to increase awareness of fetal movements does not reduce risk of stillbirth

A care package to increase awareness of fetal movements, and allow identification and delivery of high-risk babies, did not reduce the risk of stillbirth. The incidence of stillbirth varies across high-income countries suggesting that many could be preventable. The AFFIRM trial is the largest to date to assess whether interventions that increase awareness of fetal ...

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Several antibiotics appear effective against early-stage Lyme disease

Most cases of Lyme disease, which is an infection carried by ticks, can be easily managed if treated early using antibiotics, with choice of antibiotic agent having little bearing on success. This network meta-analysis suggests that when symptoms of the disease are confined to a localised skin infection, treatment failures are relatively infrequent, only 2% ...

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London 2012 Olympics regeneration had minimal impact on physical and mental health

The London 2012 Olympic and Paralympic Games had only small and transient effects on physical activity, mental health and well-being for those living nearby. Although access to sporting facilities and green space improved, local adolescents and their parents did not receive any sustained positive effect on physical activity, mental health or well-being. This NIHR-funded study assessed ...

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Standing desks with a support package reduce time sitting at work

An office-based intervention involving a height-adjustable workstation and instruction package reduced the amount of time spent sitting. Workers sat for around 60 to 90 minutes less per day at six and 12 months compared with the control group. Sitting for long periods is a risk factor for ill health even in people meeting recommended levels ...

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Antibiotics may be an alternative first-line treatment for uncomplicated appendicitis

Appendicectomy surgery could potentially be avoided for around 60% of adults with uncomplicated appendicitis if they receive antibiotics first. Adults in Finland with appendicitis were randomised to have appendicectomy or a course of antibiotics. In 6 out of 10 the appendicitis settled and did not return over the five years they were followed. Of those ...

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Radiotherapy benefits some men whose prostate cancer has spread to their bones

Adding radiotherapy directed at the prostate to hormone treatment for all men with metastatic prostate cancer makes no difference to overall survival. However, when men with a limited number of metastases confined to the bones of the pelvis and spine are treated with radiotherapy to the prostate, their survival improves. The standard treatment for men ...

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