Evidence
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Extending breast screening to women in their forties may save lives without increasing harms, research suggests

Around 7,600 women in their 40s are diagnosed with breast cancer every year in the UK. But the NHS Breast Screening Programme only starts inviting women once they turn 50. Mammography (X-ray of the breasts) is offered to women every three years between the ages of 50 to 70. There is long-standing debate about the ...

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To improve team decision-making in cancer care: streamline workload, shorten meetings, address logistics and keep a gender balance on the team

For the past 20 years, the cornerstone of cancer care has been Multidisciplinary Teams (MDTs) who meet regularly to discuss the treatment and progress of people with cancer and plan the next steps. MDTs bring together a wide range of healthcare professionals, including surgeons, radiologists, oncologists, cancer nurse specialists and histopathologists (who examine samples of ...

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People with anaemia may not benefit from iron therapy ahead of major abdominal surgery, research finds

People with anaemia who were due to have major abdominal surgery did not see the expected benefits from receiving iron infusions in advance. A new study found that iron infusions did not reduce blood transfusions or deaths compared to a dummy treatment with salt water (placebo). There was no reduction in complications while people were ...

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An innovative swallowable sponge detects Barrett's oesophagus in people with heartburn, study shows

Detection of a pre-cancerous throat condition called Barrett’s oesophagus can be improved with the use of an innovative swallowable sponge and laboratory test, a large multicentre trial found. Heartburn, caused by acid reflux from the stomach up into the gullet (oesophagus), is common among people visiting their GP. It is usually treated with acid suppressants. ...

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Active monitoring in early prostate cancer prevents as many deaths as surgery or radiotherapy, new research shows

A long-running clinical trial of how best to treat men diagnosed with early prostate cancer found that active monitoring was as effective as surgery or radiotherapy in preserving life. Active monitoring, sometimes called 'watch and wait', means that men have regular tests, and only have surgery or radiotherapy if the cancer progresses. In the trial, ...

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Theatre can bring research findings to life for a wide range of audiences

Traditional academic methods of communicating research findings often fail to reach key audiences including patients, or professionals from different disciplines. BRIGHTLIGHT is a national research project looking at whether specialist cancer services for teenagers and young people add value. The researchers wanted young people to know about their results, along with audiences often not reached ...

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Rituximab improves survival in children with non-Hodgkin’s lymphoma

Children with an aggressive cancer of the lymphatic system may benefit from a new treatment regime. New findings from an international trial show that adding a drug called rituximab to standard doses of chemotherapy significantly improves young people’s survival. Non-Hodgkin’s lymphoma is a cancer that develops in the lymphatic system, a network of vessels and ...

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People with thyroid cancer who are asked to follow a low iodine diet need clear information

People with thyroid cancer who were asked to adjust their diet ahead of treatment, were confused about what they needed to do. The first UK study of these patients’ experiences found that many restricted their diet more and for longer than is advised. Some reported conflict or distress associated with the diet and were anxious ...

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Women with cancer of the stomach or oesophagus are more likely to survive than men, but they have worse side effects from chemotherapy

Women treated for cancer of the stomach or oesophagus (the muscular tube which moves food from mouth to stomach) may survive longer than men. An analysis of over 3000 patients with these cancers also found that women experienced more nausea, vomiting, and diarrhoea during therapy. Cancer-related survival was the same for older (70 or over) ...

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First-line chemotherapy for ovarian cancer given once every three weeks may preserve quality of life

Women with a new diagnosis of ovarian cancer receiving weekly chemotherapy may have reduced quality of life compared to those receiving treatment every three weeks because the more frequent treatment may cause long-lasting nerve damage. Ovarian cancer is usually treated every three weeks with chemotherapy containing the medicines carboplatin and paclitaxel. A study in Japan ...

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