Evidence
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Results from a routine blood test could help in early detection of cancer

Detecting cancer at the earliest opportunity can improve the chances of successful treatment.  New research suggests that a routine blood test could help find cancers early. Researchers have previously shown that high levels of platelets – cells in the blood that help stop bleeding – can be a sign of cancer. But now they have ...

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People with anorectal melanoma may not benefit from radical surgery

New research suggests that limited surgery is preferable to radical surgery for a rare and aggressive type of cancer called anorectal melanoma. This cancer starts in the anus or rectum (back passage). In limited surgery (wide local excision or WLE), the cancer and a small area around it is removed. In more radical surgery (abdominoperineal ...

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More precise classification of risk in prostate cancer reveals a huge variation in treatment

A new study found a wide variation in how men with prostate cancer are managed in different hospitals. Current NICE guidelines recommend that prostate cancers are broadly classified into those at low, intermediate or high risk of spreading. A more precise system for classifying risk revealed that hospitals may have different approaches for managing men ...

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Cultural and language barriers need to be addressed for British-Pakistani women to benefit fully from breast screening

British-Pakistani women may need help to overcome cultural and language barriers if they are to fully take part in the NHS breast screening programme. Breast screening uses an X-ray test called a mammogram to spot cancers when they are too small to see or feel. UK women aged 50 to 70 years receive an invitation ...

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Screening for lymphoedema after breast cancer surgery could identify women likely to benefit from compression sleeves

Some women having breast cancer surgery would benefit from screening to pick up lymphoedema (swelling of the arm that can become long-term). This can develop as a complication of surgery if lymph nodes are removed. Lymph nodes under the arm normally drain fluid from the breast. They may be removed during breast cancer surgery to ...

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GPs who make the most urgent referrals for cancer see the fewest cancer deaths among their patients

GP practices across England vary in how frequently they make urgent referrals for suspected cancer. Patients from general practices which make the most urgent referrals are more likely to have their cancer diagnosed at an early stage. A new study found that they are about 4% less likely to die within 5 years. This is ...

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High-intensity interval training rapidly improves fitness in patients awaiting surgery for urological cancer

High-intensity interval training (HIIT) significantly improved men’s fitness in the short timeframe before cancer surgery. A small study found that HIIT improved the heart and lung (cardiorespiratory) function of men with urological cancers such as of the prostate, bladder or kidney. The authors hope their findings will lead to the development of effective exercise regimes ...

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Largest ever trial into a rare cancer of the urinary system shows clear benefits of chemotherapy after surgery

A rare cancer of the urinary system can be effectively treated with chemotherapy after surgery. The largest trial ever conducted into the disease found that giving chemotherapy halves the risk of the cancer coming back after surgery. The results provide clear evidence for this approach to become the new standard of care for patients whose ...

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Cancer screening across the world is failing people with mental illness

People with mental illness are nearly 25% less likely to receive cancer screening than those in the general population. Results from a large international study suggest this is one explanation for why people with mental illness tend to die 15-20 years earlier than other people. The study included more than 4.5 million people across the ...

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Text messaging support helps smokers quit, but apps not yet shown to work

Text messaging support helps people quit smoking, more than minimal support such as self-help materials. Also, when text messaging is combined with another smoking cessation intervention, it is more effective than just that intervention alone. However, the evidence to support smartphone apps is absent or of poor quality. This review included 26 studies and builds ...

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