Evidence
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A combination of tests is needed to diagnose a dangerous type of meningitis in children

Meningitis caused by tuberculosis (TB) is rare in the UK, but it is a dangerous disease which can be fatal or leave people with disabilities. Children are particularly vulnerable to poor outcomes. TB is better known for causing lung disease, but the bacteria can also infect the brain, causing TB meningitis. The disease is often ...

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Aspirin could reduce the risk of heart attack or stroke in people with pneumonia, research suggests

People with pneumonia are at high risk of having a heart attack or stroke. New research suggests that taking aspirin may reduce the risk of these cardiovascular events. Pneumonia is swelling (inflammation) of the tissue in one or both lungs. It is usually caused by bacterial infection but can also be caused by viruses, including ...

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Supported self-management for people with asthma is the most effective model of care

Self-management of asthma means healthcare professionals educating, training and supporting people with asthma so they learn to manage their own condition. But there is little evidence to guide the level of support patients need from their healthcare team. This study compared four self-management models for asthma by reviewing existing research papers. The most effective model ...

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Lung health checks in supermarket car parks reach older smokers in deprived communities

Tests carried out on mobile units parked in supermarket car parks were a popular and effective way to check the lungs of at-risk current and former smokers in a study in Manchester.     Simple tests of lung function in these mobile units found more than a third of those screened had evidence of airflow obstruction. This ...

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Asthma patients with a history of opioid use have worse outcomes

A new study of asthma patients with and without a history of drug misuse found that rates of attendance at an annual asthma review were poor across the whole group. Rates of flu vaccination, which is recommended for people with asthma, were also generally low. However, patients with a history of opioid use disorders (OUD) ...

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A simple test may predict the risk of hospitalisation for flare-up in patients with COPD, a common lung disease

The sit-to-stand test, which requires only a chair and a stopwatch, could identify patients with a common lung disease who are at high risk of being admitted to hospital. Researchers found that the test, which takes less than five minutes to perform, also predicted the length of their hospital stay. The study looked at patients ...

Collection

5 ways research could save the NHS money

More than 80% of total knee replacements can last for 25 years An NIHR-funded study showed that about 82% of total knee replacements and 70% of partial (unicompartmental) knee replacements last for 25 years. In 2017 there were 106,334 knee replacement procedures carried out in England, Wales and Northern Ireland. This research suggests people could be ...

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‘As-needed’ combination asthma inhalers can be more effective than regular inhaled steroids

In adults with mild to moderate asthma, budesonide-formoterol used as needed for symptom relief was more effective at preventing severe exacerbations than maintenance low-dose budesonide plus as-needed terbutaline. In this trial involving 885 adults, those using the combination inhaler as required had fewer severe asthma attacks, with similar levels of general symptom control, and overall ...

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Holistic services in advanced lung disease can help people cope better with breathlessness

Services providing holistic health care can improve the psychological well-being of people who are living with breathlessness associated with chronic or advanced lung disease, such as lung cancer or chronic obstructive pulmonary disease. Breathlessness is a distressing symptom in which feelings of fear and helplessness, social isolation, high levels of anxiety and significant carer burden ...

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Long-term macrolide antibiotics reduce risk of exacerbations of bronchiectasis

People with bronchiectasis (not caused by cystic fibrosis) who take long-term macrolide antibiotics are around 50% less likely to experience acute worsening of symptoms like cough and sputum production (an exacerbation) than people taking a placebo. Bronchiectasis guidelines only recommend preventative macrolide antibiotics in people with frequent exacerbations who do not carry a bacterium (Pseudomonas ...

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