Evidence
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Lung health checks in supermarket car parks reach older smokers in deprived communities

Tests carried out on mobile units parked in supermarket car parks were a popular and effective way to check the lungs of at-risk current and former smokers in a study in Manchester.     Simple tests of lung function in these mobile units found more than a third of those screened had evidence of airflow obstruction. This ...

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Asthma patients with a history of opioid use have worse outcomes

A new study of asthma patients with and without a history of drug misuse found that rates of attendance at an annual asthma review were poor across the whole group. Rates of flu vaccination, which is recommended for people with asthma, were also generally low. However, patients with a history of opioid use disorders (OUD) ...

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A simple test may predict the risk of hospitalisation for flare-up in patients with COPD, a common lung disease

The sit-to-stand test, which requires only a chair and a stopwatch, could identify patients with a common lung disease who are at high risk of being admitted to hospital. Researchers found that the test, which takes less than five minutes to perform, also predicted the length of their hospital stay. The study looked at patients ...

Collection

5 ways research could save the NHS money

More than 80% of total knee replacements can last for 25 years An NIHR-funded study showed that about 82% of total knee replacements and 70% of partial (unicompartmental) knee replacements last for 25 years. In 2017 there were 106,334 knee replacement procedures carried out in England, Wales and Northern Ireland. This research suggests people could be ...

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Holistic services in advanced lung disease can help people cope better with breathlessness

Services providing holistic health care can improve the psychological well-being of people who are living with breathlessness associated with chronic or advanced lung disease, such as lung cancer or chronic obstructive pulmonary disease. Breathlessness is a distressing symptom in which feelings of fear and helplessness, social isolation, high levels of anxiety and significant carer burden ...

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‘As-needed’ combination asthma inhalers can be more effective than regular inhaled steroids

In adults with mild to moderate asthma, budesonide-formoterol used as needed for symptom relief was more effective at preventing severe exacerbations than maintenance low-dose budesonide plus as-needed terbutaline. In this trial involving 885 adults, those using the combination inhaler as required had fewer severe asthma attacks, with similar levels of general symptom control, and overall ...

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Long-term macrolide antibiotics reduce risk of exacerbations of bronchiectasis

People with bronchiectasis (not caused by cystic fibrosis) who take long-term macrolide antibiotics are around 50% less likely to experience acute worsening of symptoms like cough and sputum production (an exacerbation) than people taking a placebo. Bronchiectasis guidelines only recommend preventative macrolide antibiotics in people with frequent exacerbations who do not carry a bacterium (Pseudomonas ...

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Clinicians prescribe antibiotics for childhood respiratory tract infection based on assessment, rather than parental expectation

Implied parental expectation of antibiotic prescription does not appear to affect clinician prescribing for childhood respiratory tract infection in primary care. Parents typically accept clinicians’ treatment recommendations based on symptoms and signs, with a minority seeking further home care advice. This NIHR-funded analysis of 56 videoed primary care consultations is the first such study to ...

Collection

My Signals - Occupational Therapy

In My Signals, health and social care staff and service users tell us what research is important to them and why they feel others need to know about it. In this collection, we asked seven occupational therapists to tell us which Signals have interested them most and explain why they feel the findings are worth ...

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High-flow nasal oxygen reduces reintubation after major surgery compared with conventional oxygen therapy

In adults after major surgery, high-flow nasal oxygen decreases by about two-thirds the need for reintubation compared with conventional oxygen therapy. In this study, only about four in every 100 patients needed reintubation with high-flow nasal oxygen, compared with about 11 in every 100 patients receiving conventional oxygen therapy. This review evaluated seven randomised and ...

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