Evidence
Collection

My Signals - Public Health Collection

In My Signals, health and social care staff and service users tell us what research is important to them and why they feel others need to know about it. Join the conversation on Twitter and tell us which Signals have interested, excited or surprised you, using #MySignals. You can find the latest NIHR Signals here. In this collection, Dr Rupert ...

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Blood test and ECG may safely rule out heart attack

A high sensitivity troponin test accurately ruled out a heart attack amongst a third of patients presenting to the emergency department with chest pain. A patient with no detectable troponin and normal electrocardiogram was almost certain not to have had a heart attack. Many people come to hospital with chest pain, but more than 75% ...

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52-week programme leads to more weight loss than 12-week

Obese people referred to a 52-week group weight management programme lost about 2kg more weight on average by one and two years compared to those referred for the standard 12 weeks. These modest health gains were also more likely to be sustained over time in the long programme. A brief intervention led to 3kg weight ...

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Use of public defibrillators linked to out-of-hospital cardiac arrest survival

Providing a shock using a defibrillator to people with out-of-hospital cardiac arrest before the arrival of emergency medical services increases their chance of survival. The UK survival rate is around 8%, which is lower than in other developed countries. This review found that bystander assistance through cardiopulmonary resuscitation and attaching a defibrillator increased it to ...

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Resistance training may prevent obese older people becoming frail when losing weight

Combining resistance training with aerobic exercise increased physical function in older, obese adults who were following a weight loss programme. Functional improvements, such as the speed to stand from a chair or to climb stairs, were greater with combination training (21%) than with either type of exercise performed alone (14%). This randomised controlled trial assigned ...

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Comprehensive assessment may reduce risk of delirium after hip fracture

Comprehensive geriatric assessment reduced the risk of delirium by 20% in patients having hip fracture surgery. Forty-three percent developed delirium on average compared with 53% who didn’t receive these assessments. The assessment of the older persons’ medical condition was typically undertaken by a team of healthcare professionals who assessed functional ability, living circumstances and risk ...

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Molluscum contagiosum is best left to clear by itself

Molluscum contagiosum, the viral skin infection, is best left alone to heal by itself rather than being treated with medication, destructive treatments or creams. When comparing imiquimod (a skin cream that activates the immune system) with nothing, about 40% of people were clinically clear by 6 months in either group. Treatment increased the chance of ...

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Teaching sexual health at school improved knowledge but not safe sex practices

School-based sexual health interventions improved knowledge and attitudes in school students up to 18. However, they failed to consistently improve safe sex practices or reduce unwanted pregnancies. Abstinence-based messages were least effective. This review of reviews included 37 systematic reviews of school-based sexual health interventions. It excluded low-quality reviews and spanned 1990 to 2016, so ...

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Carers of stroke survivors voice an unmet need for practical and emotional support

The carers of stroke survivors express a need to be recognised by hospital rehabilitation teams as partners in care. Carers emphasised that their deep knowledge can contribute to joint decision making about the care of their spouse or family member. This research suggests that considering carers’ needs for support, information and training into care planning ...

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Drug reduces deaths from bleeding after childbirth

Tranexamic acid, given to women who bleed heavily after giving birth, reduced the risk of death by 31% when given within three hours. This trial included 20,060 women with postpartum haemorrhage who were randomly assigned to receive tranexamic acid or placebo. This is the first large study to indicate that it is safe and implies ...

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