Evidence
Themed Review

Living with Covid19

A dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid). Key Messages Introduction What are we aiming to achieve with our Living with Covid19 review? Drawing on people’s experience How many people live with ongoing Covid19? Symptoms Diagnostic uncertainty Research into living with Covid19 Capturing the experience of ‘Long Covid’ Services ...

Alert

Brain and nerve complications are more common than expected in younger patients with severe COVID-19

People aged under 60 who are hospitalised with COVID-19 are more likely than expected to experience severe psychiatric symptoms. Research found that altered mental states such as psychosis are being reported in these younger patients.  It confirmed that strokes and other neurological symptoms are common in severe COVID-19. An initial study included 153 cases reported ...

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Tackling fear and misinformation may help increase hepatitis C testing in prison

Liver disease caused by the hepatitis C virus (HCV) is a major public health burden. The World Health Organisation is aiming to eliminate HCV as a public health problem by 2030 and testing in prisons is central to this campaign. People entering prison are asked to have a test for blood-borne viruses including HCV, but ...

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Community-based medicine collection improves access to lifesaving HIV treatment in South Africa

A programme in South Africa is successfully shifting the location of treatments for long term conditions from the clinic to the community. It is the largest programme of its kind in the world and a new study highlights the benefits to people living with HIV. The programme is called Centralised Chronic Medication Dispensing and Distribution ...

Collection

Mental health and COVID-19

The impact of COVID-19 pandemic and the constraints it has imposed on people is an issue of interest and concern to patients, service users, carers and health and social care professionals alike. In pandemic conditions it is likely that people’s existing mental health problems may get worse. Mental health may also decline because of social ...

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High rates of delirium, persistent fatigue and post-traumatic stress disorder were common after severe infection in previous coronavirus outbreaks

Little is known about the mental health consequences of severe COVID-19 illness because it is caused by a new coronavirus. Previous outbreaks caused by other coronaviruses (severe acute respiratory syndrome, SARS, and Middle East respiratory syndrome, MERS) may provide insights into ongoing problems after recovery from severe illness.  Researchers looked at reports of psychiatric problems ...

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Measles vaccine still effective if given to infants under nine months old

A first vaccination dose against measles is a safe and somewhat effective option if given to infants earlier than usual, and before the age of nine months. However, vaccine effectiveness does increase when administered at older ages, as currently. Two doses of measles-containing vaccines are recommended as part of a childhood immunisation programme. In countries ...

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Uptake of shingles vaccination is more likely if proactively offered in primary care

The shingles vaccination programme is intended for people aged between 70 and 80 years, but uptake in this group has been low. This survey found that people were more likely to have had the vaccine if it was proactively offered by a GP or nurse. The survey was completed by 536 individuals born in 1934 ...

Collection

My Signals - Patients, 2019

In My Signals, health and social care staff and service users tell us what research is important to them and why they feel others need to know about it. In this collection, we asked seven members of the public to tell us which Signals have interested them most and explain why they feel the findings ...

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Herpes zoster vaccine reduces chances of shingles after stem cell transplants

A non-live vaccine against herpes zoster provides good, though partial protection for adults undergoing autologous (using the patient’s own) stem cell transplant for treatment of blood cancers. These people cannot use the usual live vaccine, because of their suppressed immune system. An industry-funded trial of the vaccine involved 1,846 patients from 28 countries, including the ...

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