Evidence
Collection

Clinical decision support tools

Clinical decision support tools aim to improve healthcare delivery by enhancing decision making through the provision of targeted health information. The evolution of clinical decision support tools has been boosted by the introduction of new technologies, and their evaluation as useful resources continues to be an area of high interest for health professionals. This Collection ...

Themed Review

Living with Covid19

A dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid). Key Messages Introduction What are we aiming to achieve with our Living with Covid19 review? Drawing on people’s experience How many people live with ongoing Covid19? Symptoms Diagnostic uncertainty Research into living with Covid19 Capturing the experience of ‘Long Covid’ Services ...

Alert

Results from a routine blood test could help in early detection of cancer

Detecting cancer at the earliest opportunity can improve the chances of successful treatment.  New research suggests that a routine blood test could help find cancers early. Researchers have previously shown that high levels of platelets – cells in the blood that help stop bleeding – can be a sign of cancer. But now they have ...

Alert

Brain and nerve complications are more common than expected in younger patients with severe COVID-19

People aged under 60 who are hospitalised with COVID-19 are more likely than expected to experience severe psychiatric symptoms. Research found that altered mental states such as psychosis are being reported in these younger patients.  It confirmed that strokes and other neurological symptoms are common in severe COVID-19. An initial study included 153 cases reported ...

Alert

Prozac may be the best treatment for young people with depression – but more research is needed

Children and adolescents with moderate-to-severe depression are being prescribed treatments that are not backed by reliable evidence. There is insufficient data on whether treatments work and if they are safe. Unlike for adults, the best way to treat symptoms of depression in these age groups is unknown. A review of 71 separate trials found that ...

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Play and social skills may protect children who have difficulties with spoken language

Children with developmental language disorder (DLD) have ongoing difficulties with spoken language. They may struggle to understand long sentences, to tell stories or to take turns in a conversation.  The disorder makes communication difficult and can slow children’s progress at school. Their self-esteem can be harmed and, overall, children with DLD have poorer mental health ...

Alert

Working may improve quality of life for carers of people with dementia

Those who care for people with dementia are likely to report a better quality of life if they also work outside the home. This may be linked to higher self-esteem. A study included almost 1,300 people caring for relatives with dementia. It found that carers with jobs outside the home were likely to be younger ...

Alert

A decision aid may help people with newly-diagnosed multiple sclerosis consider their options for treatment

When first diagnosed with multiple sclerosis (MS), people may feel overwhelmed with information, or too shocked by the diagnosis to fully engage with decisions about treatment. New research found that decision aids may help them to understand their condition and make decisions that are right for them.  Treatments for people with MS can improve long-term ...

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People with anorectal melanoma may not benefit from radical surgery

New research suggests that limited surgery is preferable to radical surgery for a rare and aggressive type of cancer called anorectal melanoma. This cancer starts in the anus or rectum (back passage). In limited surgery (wide local excision or WLE), the cancer and a small area around it is removed. In more radical surgery (abdominoperineal ...

Alert

A new technique could make more livers available for transplant

Demand for liver transplants is so high that many people on the waiting list die before they can receive a transplant. But surgeons are rejecting increasing numbers of donated livers because they are not satisfied with the quality. New research could address this problem and make more livers available for transplant. Current practice is for ...

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