Evidence
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Schools can provide valuable help for children with attention deficit hyperactivity disorder

This series of NIHR-funded systematic reviews found that some things schools do (interventions) can help children with attention deficit hyperactivity disorder. These were grouped into 15 main approaches including reward and punishment, skills training and self-management, creative-based therapies, such as music therapy, and structured physical activity. These reviews covered different strategies to change behaviour other ...

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A single dose of diclofenac potassium is more effective for postoperative pain than the more commonly used diclofenac sodium

This Cochrane systematic review found that the same single dose of fast-acting diclofenac potassium tablets is more effective for moderate to severe short-term postoperative pain relief than coated diclofenac sodium tablets. Both versions were compared with a placebo, rather than each other. On average, only two people need to be treated with a single dose ...

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Blowing up a balloon with the nose helps restore hearing in children with glue ear

The use of a simple nasal balloon can help restore hearing in children aged 4 to 11 with glue ear. After 3 months, this non-surgical treatment restored normal hearing to 49.6% of children with glue ear compared with 38.3% receiving usual care. Children inflate the balloon by blowing it up with their noses rather than their ...

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Case management might not improve health outcomes or reduce costs

This systematic review of trials found that case management in primary care of people at risk of unplanned hospital admission did not improve health outcomes, mortality, use of healthcare services, or save money. Patient satisfaction improved, but only a little. Case management was defined as the identification, assessment and care-coordination of people at risk of ...

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Drug therapy after a coronary stent should be tailored to patient’s risk profile

This systematic review tried to find the optimal duration of dual antiplatelet therapy, usually aspirin and clopidogrel, after coronary stenting. Compared to standard antiplatelet therapy for 12 months, shorter treatment had little impact on stent thrombosis. Treatment for longer than 12 months did, however, reduce thrombosis by 67% (about 7 events per 1000 people).  Major ...

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Centralising stroke services improves chances of patients getting the right care

This study of two models of organising stroke care showed that fully centralised services were more likely to deliver clinically effective treatments. This NIHR-funded study looked at stroke care audit data before and after introducing two different models of centralised stroke services in London and Manchester. The audit recorded the proportion of stroke patients in ...

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Education and support groups help carers of people with severe mental illness

This systematic review found that carer-focused interventions can improve the experience of caring, carer quality of life and reduce psychological distress in those caring for people with severe mental illness in the community. Psychoeducationand support group style interventions delivered by health and social care services led to improvements in carer outcomes such as how positively ...

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Comparing blood tests to detect diabetes during NHS health checks

This NIHR-funded study estimated the long-term cost effectiveness of using two recommended blood tests – glycated haemoglobin or fasting blood glucose - to detect type 2 diabetes during NHS health checks. Several screening strategies were tested. In most cases the glycated haemoglobin test was more likely to be cost effective than a fasting blood glucose. ...

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Occupational therapy several years after stroke does not improve function in severely ill care home residents

This trial found that a three-month individualised occupational therapy programme did not significantly improve the daily functioning (dressing, using the toilet and overall mobility) of severely physically and cognitively impaired people living in residential care who had a stroke on average three years before. About a quarter of stroke survivors in the UK cannot return ...

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Resveratrol supplements do not improve cardiovascular risk markers

This systematic review of trials found that resveratrol supplements do not improve the results of tests that indicate risk of heart disease, including levels of blood pressure, blood glucose, cholesterol or C-reactive protein. Resveratrol is found naturally in red grapes, other fruits, and nuts. Some researchers think resveratrol in red wine may lower the risk ...

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