Evidence
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Adults who are more active live longer

People who are more physically active in middle age are less likely to die early, whether they do light or moderate to vigorous activity. The largest reductions in death are seen for those who do around 375 minutes a day of light intensity physical activity, such as walking, cooking or gardening, or 24 minutes a ...

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Losing weight following type 2 diabetes diagnosis boosts chance of remission

People who lose at least 10% of their body weight in the first year after being diagnosed with type 2 diabetes increase their chances of being in remission after five years, compared with those whose weight remains stable. Losing this achievable amount of weight over the next four years also makes remission more likely. In ...

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Combined drug therapy for at least 36 weeks reduces relapse after psychotic depression

Patients with psychotic depression who achieve remission benefit from continuing the antipsychotic drug olanzapine, alongside the antidepressant sertraline for at least a further four months, a North American trial has found. Patients who reduced and stopped olanzapine when their condition stabilised were more than twice as likely to relapse when compared with those who continued ...

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Telephone-delivered CBT can provide lasting benefits for people with IBS

People with irritable bowel syndrome (IBS) who receive cognitive behavioural therapy (CBT) continue to have lower levels of symptoms over the following two years. Telephone-delivered CBT is particularly effective, with 71% of study participants experiencing a clinically significant improvement in their IBS symptoms. This NIHR-funded study is the 24-month follow-up to an earlier publication of ...

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Planned earlier delivery for late pre-eclampsia may be better for mothers

If pregnant women develop late pre-eclampsia, after 34 but before 37 weeks of gestation, then planning to deliver their babies within 48 hours of the diagnosis reduces the risk of problems to the mother. This is compared with waiting until 37 weeks or delivering earlier if other problems arise (“expectant management”). However, this benefit needs ...

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Patients, in theory, might prefer GP-led care to self-management for high blood pressure

Patients offered the pros and cons of different monitoring options appear reluctant to self-manage high blood pressure, and prefer frequent monitoring by a GP, pharmacist or via telehealth (where readings are sent to health professionals and medicines managed remotely). The small online survey, completed by 167 patients, was used to explore how patients might feel ...

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A workplace voucher reward scheme failed to boost physical activity

Staff enrolled on a workplace reward scheme to encourage them to become more physically active took fewer steps per day than their colleagues in the control group after six months. Employees at two public sector organisations in Northern Ireland took part in the Physical Activity Loyalty scheme, which worked in a similar way to a ...

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Boosting omega-3 fatty acid intake is unlikely to prevent type 2 diabetes

Increasing the intake of polyunsaturated fats in the diet with supplements of omega-3 fatty acids, for example, is unlikely to affect people’s risk of developing type 2 diabetes. However, this review only looked at the effect of supplements on diabetes, not wider health. This large systematic review included 83 long-term trials comparing higher and lower ...

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Keyhole hysterectomy is effective for women with heavy menstrual bleeding

When surgical treatment was needed, almost all women with heavy menstrual bleeding were satisfied and had a good quality of life following keyhole surgery to remove the uterus. Slightly fewer achieve this with ablation to remove the uterine lining. In a UK randomised trial, women given one or other treatment in NHS hospitals reported good ...

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Herpes zoster vaccine reduces chances of shingles after stem cell transplants

A non-live vaccine against herpes zoster provides good, though partial protection for adults undergoing autologous (using the patient’s own) stem cell transplant for treatment of blood cancers. These people cannot use the usual live vaccine, because of their suppressed immune system. An industry-funded trial of the vaccine involved 1,846 patients from 28 countries, including the ...

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