Evidence
Themed Review

Moving Forward - A Guide for the Public

                Download the PDF A guide for the public on the latest physiotherapy research for the health and wellbeing of people with muscle, bone and joint pain This was published in association with the Chartered Society of Physiotherapy, Keele University and Versus Arthritis. All information in these materials ...

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With the right training, people with learning disabilities can become partners in research

A training course for students with learning disabilities succeeded in increasing their knowledge of research and their research skills. The course also increased their confidence and self-esteem. Several of the students went on to take up new work opportunities. The authors recommend that funding should be made available to help run more of these courses ...

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New research provides insights into the distress experienced by transgender adults

Transgender people have a mismatch between their sex assigned at birth and the gender they identify as. This can lead to sense of unease, dissatisfaction or distress (gender dysphoria) which can be intense. Social factors also cause negative feelings. Treatment at gender clinics is only available to those who have gender dysphoria. How gender dysphoria ...

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Community-based medicine collection improves access to lifesaving HIV treatment in South Africa

A programme in South Africa is successfully shifting the location of treatments for long term conditions from the clinic to the community. It is the largest programme of its kind in the world and a new study highlights the benefits to people living with HIV. The programme is called Centralised Chronic Medication Dispensing and Distribution ...

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Anti-inflammatory drugs do not lift depression in bipolar disorder

Two drugs which are often used to treat inflammation failed  to help people with bipolar depression. Previous research has suggested that inflammation of the brain may be involved in some mental illnesses, including depression. It meant that drugs which block inflammation could potentially be a new way of treating depression. But the first large clinical ...

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Drug users who lack access to clean water use dangerous alternatives to prepare injections

Strategies to reduce the harm to homeless people who inject drugs rarely focus on their lack of access to clean water. This matters because injecting drugs prepared with unclean water or alternatives to water can lead to serious infections and illness. A study explored how people who inject drugs typically prepare injections, including when they ...

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Melatonin shows potential for reducing delirium among older people after surgery

Taking melatonin around the time of surgery is linked with lower odds of delirium onset in older people, compared with placebo or no treatment. In a systematic review and meta-analysis, around 15% of the melatonin group developed delirium after surgery compared with around 20% of the comparison group. Delirium is an acute state of mental ...

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Structured nurse ward rounds support accountability and risk management but not nurse-patient communication

Scheduling regular nurse bedside ward rounds (called ‘intentional rounding’) may not improve nurse-patient communication, as most interactions occur outside of these rounds. The rounds are intended to improve accountability and provide evidence that risks are being managed when correctly documented. Intentional rounding was introduced as a UK Government policy imperative to facilitate regular interactions between ...

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Antenatal MRI can aid ultrasound when fetal brain abnormality is suspected

In utero magnetic resonance imaging (iuMRI) can provide a more accurate diagnosis when used after ultrasound in pregnancy. Adding iuMRI when a brain abnormality is suspected but unclear from ultrasound could help clinicians provide better prognostic advice and support to parents during pregnancy. This NIHR-funded cohort study compared ultrasound and iuMRI in 570 women at ...

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Group cognitive behavioural courses may reduce fatigue from rheumatoid arthritis

Fatigue can be one of the most difficult symptoms to cope with for people with rheumatoid arthritis and this study found that group cognitive behavioural courses may help. This NIHR-funded study compared six weekly group sessions plus a booster session with a single brief one-to-one meeting. Both groups also received an educational booklet. It took ...

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