Evidence
Alert

Brain and nerve complications are more common than expected in younger patients with severe COVID-19

People aged under 60 who are hospitalised with COVID-19 are more likely than expected to experience severe psychiatric symptoms. Research found that altered mental states such as psychosis are being reported in these younger patients.  It confirmed that strokes and other neurological symptoms are common in severe COVID-19. An initial study included 153 cases reported ...

Alert

Prozac may be the best treatment for young people with depression – but more research is needed

Children and adolescents with moderate-to-severe depression are being prescribed treatments that are not backed by reliable evidence. There is insufficient data on whether treatments work and if they are safe. Unlike for adults, the best way to treat symptoms of depression in these age groups is unknown. A review of 71 separate trials found that ...

Alert

Play and social skills may protect children who have difficulties with spoken language

Children with developmental language disorder (DLD) have ongoing difficulties with spoken language. They may struggle to understand long sentences, to tell stories or to take turns in a conversation.  The disorder makes communication difficult and can slow children’s progress at school. Their self-esteem can be harmed and, overall, children with DLD have poorer mental health ...

Alert

Working may improve quality of life for carers of people with dementia

Those who care for people with dementia are likely to report a better quality of life if they also work outside the home. This may be linked to higher self-esteem. A study included almost 1,300 people caring for relatives with dementia. It found that carers with jobs outside the home were likely to be younger ...

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A decision aid may help people with newly-diagnosed multiple sclerosis consider their options for treatment

When first diagnosed with multiple sclerosis (MS), people may feel overwhelmed with information, or too shocked by the diagnosis to fully engage with decisions about treatment. New research found that decision aids may help them to understand their condition and make decisions that are right for them.  Treatments for people with MS can improve long-term ...

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People with anorectal melanoma may not benefit from radical surgery

New research suggests that limited surgery is preferable to radical surgery for a rare and aggressive type of cancer called anorectal melanoma. This cancer starts in the anus or rectum (back passage). In limited surgery (wide local excision or WLE), the cancer and a small area around it is removed. In more radical surgery (abdominoperineal ...

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A new technique could make more livers available for transplant

Demand for liver transplants is so high that many people on the waiting list die before they can receive a transplant. But surgeons are rejecting increasing numbers of donated livers because they are not satisfied with the quality. New research could address this problem and make more livers available for transplant. Current practice is for ...

Themed Review

Moving Forward - A Guide for the Public

                Download the PDF A guide for the public on the latest physiotherapy research for the health and wellbeing of people with muscle, bone and joint pain This was published in association with the Chartered Society of Physiotherapy, Keele University and Versus Arthritis. All information in these materials ...

Alert

Tackling fear and misinformation may help increase hepatitis C testing in prison

Liver disease caused by the hepatitis C virus (HCV) is a major public health burden. The World Health Organisation is aiming to eliminate HCV as a public health problem by 2030 and testing in prisons is central to this campaign. People entering prison are asked to have a test for blood-borne viruses including HCV, but ...

Alert

Tranexamic acid should not be used for patients with severe gastrointestinal bleeding

A drug called tranexamic acid is used to control severe bleeding caused by injury or childbirth. Some doctors had also started using it to treat patients with severe gastrointestinal (GI) bleeding, which is a common medical emergency. Evidence from small trials had suggested it could reduce deaths. The HALT-IT (Haemorrhage alleviation with tranexamic acid-Intestinal system) ...

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