Evidence
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Community-based medicine collection improves access to lifesaving HIV treatment in South Africa

A programme in South Africa is successfully shifting the location of treatments for long term conditions from the clinic to the community. It is the largest programme of its kind in the world and a new study highlights the benefits to people living with HIV. The programme is called Centralised Chronic Medication Dispensing and Distribution ...

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Screening for lymphoedema after breast cancer surgery could identify women likely to benefit from compression sleeves

Some women having breast cancer surgery would benefit from screening to pick up lymphoedema (swelling of the arm that can become long-term). This can develop as a complication of surgery if lymph nodes are removed. Lymph nodes under the arm normally drain fluid from the breast. They may be removed during breast cancer surgery to ...

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Group cognitive behavioural courses may reduce fatigue from rheumatoid arthritis

Fatigue can be one of the most difficult symptoms to cope with for people with rheumatoid arthritis and this study found that group cognitive behavioural courses may help. This NIHR-funded study compared six weekly group sessions plus a booster session with a single brief one-to-one meeting. Both groups also received an educational booklet. It took ...

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Telephone-delivered CBT can provide lasting benefits for people with IBS

People with irritable bowel syndrome (IBS) who receive cognitive behavioural therapy (CBT) continue to have lower levels of symptoms over the following two years. Telephone-delivered CBT is particularly effective, with 71% of study participants experiencing a clinically significant improvement in their IBS symptoms. This NIHR-funded study is the 24-month follow-up to an earlier publication of ...

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New insights into living with inflammatory bowel disease

Living with inflammatory bowel disease as a `hidden’ condition can lead to feelings of isolation and exclusion. These experiences are characterised by exhaustion, feelings of damaged body image, loss of control and living with the fear of complications. The condition can be unpredictable and have a profound impact on quality of life, disrupting social relationships ...

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Self-testing kits increase overall HIV testing uptake in men who have sex with men

Frequency of HIV testing in men who have sex with men may be increased by one additional test in a six month period when self-testing kits are used. Self-testing kits allow people to collect their finger-prick or saliva sample, perform the test and interpret the result themselves. This global study found that first-time testers made ...

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Stopping biological drugs for rheumatoid arthritis can lead to twice the relapse rate

It seems safer to reduce the dose of biological drugs, rather than to stop them if people with rheumatoid arthritis and their doctors want to avoid relapse. Stopping these powerful drugs caused the disease to recur in 58% of people compared with 29% who continued them. Reducing the dose also led to more relapses for ...

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Starting antiretroviral therapy immediately after HIV diagnosis reduces transmission of the virus

Giving antiretroviral therapy to people newly diagnosed with HIV may be an effective and cost-effective way of reducing new infections. Increased HIV testing in at-risk populations may identify more people for treatment and also reduce infection rates. Using data from a number of sources including NIHR funded projects, researchers developed a computer simulation model. The ...

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Exercise improves symptoms and function for people with ankylosing spondylitis

People with ankylosing spondylitis showed improvement in their symptoms and their ability to perform day-to-day tasks when they did more exercise. Symptom and function scores improved by almost one point on a 10-point scale after 3 to 12 weeks of exercise. Ankylosing spondylitis is a type of arthritis which mainly affects the spine, causing pain, ...

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Individual support of nurses using electronic medicine monitors can improve HIV treatment

Use of electronic pill bottles that record when they are opened and follow-up discussion of the printed readouts with nurses improved HIV outcomes. It is thought that patients became more reliable in taking the medication, which can have complicated scheduling. Overall, the HIV virus in the blood and the risk of treatment failure were lower ...

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